Archer™ VARIANTPlex™ BRCA panels
Discover important alterations for inherited disease research
Screen samples for BRCA mutations with targeted NGS. Identify SNVs, indels, and large intragenic copy number variants.
Detect confidently with Archer NGS Panels for DNA.
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Learn how the VARIANTPlex BRCA panels can identify key genomic alterations for your research.
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Panel specifications
| VARIANTPlex BRCA v3 panel | VARIANTPlex BRCA + PALB2 v2 panel | |
|---|---|---|
| Targeted genes | 2 | 3 |
| Genomic alterations | SNV, indels, intragenic CNVs | SNV, indels, intragenic CNVs |
| Input nucleic acid required* | ≥10 ng | ≥10 ng |
| Recommended number of reads | 200,000 for germline applications 1 M for somatic applications | 250,000 for germline applications 1.5 M for somatic applications |
| Hands-on time | <2.5 hours | <2.5 hours |
| Total library prep time | 1.5 days | 1.5 days |
| Platform compatibility | Illumina® | Illumina® |
| Reagent format | Lyophilized or liquid | Lyophilized or liquid |
| Supported sample types | Whole blood, saliva, FFPE | Whole blood, saliva, FFPE |
* Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.
Gene targets—VARIANTPlex BRCA v3 panel
Gene targets—VARIANTPlex BRCA + PALB2 v2 panel
Interested in adding a few genes to these panels?
Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.
Benefits
- Integrated Solution—Anchored Multiplex PCR (AMP™) chemistry paired with purpose build analysis software enables you to detect complex variants on a single solutions platform.
- Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.
- Scale easily—Liquid reagents enable automated liquid handling workflows for high volume research labs, while Anchored Multiplex PCR (AMP™) chemistry fuels reliable performance at scale.
Ready to start?
Talk with our technical sales team. Learn how the VARIANTPlex BRCA panels can identify key genomic alterations for your research.
Request a consultation